Scientists from Skoltech and the University of Potsdam have developed a physical theory that sheds light on how molecular ...

A cancer drug target already being investigated in clinical trials turns out to be doing something even more consequential ...

The human genome consists of 3 billion base pairs, and when a cell divides, it takes about seven hours to complete making a copy of its DNA. That's almost 120,000 base pairs per second. At that ...

The MCM helicase is broadly bound across the genome, and its phosphorylation is antagonistically regulated by the kinase DDK and the phosphatase RIF1–PP1. TRESLIN–MTBP recognises the phosphorylated ...

Discovery reshapes understanding of how tumor cells repair broken DNA, pointing toward more precise cancer therapies.

A graphic of a purple and magenta Cas9 protein, which is a somewhat round, but uneven, ball, bound to a yellow and orange ...

Scientists have elucidated the molecular mechanism by which LEM-3 cuts DNA bridges during cytokinesis. If DNA bridges persist between chromosomes during cell division, chromosomes are abnormally ...

Cyanobacteria—ancient microbes that oxygenated Earth and made complex life possible—are still revealing surprises billions of ...

If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by researchers at Goethe University Frankfurt, part of the Rhine-Main University ...

Shixin Liu is pioneering new ways of studying the tiny proteins that copy and read DNA in living cells. (Credit: Roshni ...