Why do human brains vary in size and shape, and how did our brains expand over evolutionary time to give us our enhanced ...

For decades, biologists treated DNA as a static string of letters, a linear code that cells read like text on a page. A new wave of research is forcing a rethink, showing that the three-dimensional ...

Researchers at The University of Texas MD Anderson Cancer Center have shown that DNA inflexibility, or rigidity, inside the nucleosome regulates the positioning of INO80. This highlights that the ...

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed. The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a ...

The landmark ideas of Watson and Crick relied heavily on the work of other scientists. What did the duo actually discover? Many people believe that American biologist James Watson and English ...

Researchers at the Nano Life Science Institute (WPI-NanoLSI) at Kanazawa University have directly visualized how enzymes find ...

It compares 'individual differences' in the sequence of ATGC, rather than looking at the shape of DNAThis also connects to ...

CRISPR is a powerful DNA-editing tool that has underpinned huge advancements in human health care in the last decade. It is a precision tool, but is not perfect, and misplaced DNA edits can compromise ...

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team. DNA is widely accepted to be formed of two strands that wind around one ...

Researchers at the Nano Life Science Institute (WPI-NanoLSI) at Kanazawa University have directly visualized how enzymes find and break DNA molecules in real time. Using high-speed atomic force ...

Researchers found how the INO80 protein moves nucleosomes to specific positions that are important for gene regulation and DNA replication INO80 uses a unique mechanism for moving nucleosomes that ...

Left panels: Atomic Force Microscopy images show how circular DNA can shift from a relaxed shape into a tightly twisted form, and how the gene-editing protein Cas9 binds to this coiled DNA (Credit: ...