A new study reveals that small cell lung cancer (SCLC) likely begins in basal stem-like cells rather than in neuroendocrine cells, marking a major shift in the understanding of this aggressive disease ...

IDH-mutant glioma, caused by abnormalities in a specific gene (IDH), is the most common malignant brain tumor among young adults under the age of 50. It is a refractory brain cancer that is difficult ...

For cancer cells to survive, grow and metastasize, they must continuously copy their DNA. Every time a cancer cell divides, it must duplicate the DNA in its chromosomes, passing one copy to each of ...

The 'cell of origin' of the second most common lung cancer and the way that it becomes dominant in the lung have been discovered, in a new study in mice and humans from researchers at UCL, the ...

A new stem-cell-inspired technique allows scientists to grow vast numbers of immune-cell progenitors that can be engineered to hunt cancer and strengthen immune responses. In animal studies, the cells ...

Survival outcomes of patients with mNSGCTs with and without teratoma in the primary tumor: An international retrospective study. Spatial transcriptional dynamics of CD74⁺ B cells in tertiary lymphoid ...

A rare but powerful branch of the human immune system is drawing renewed attention from cancer researchers, and a new review ...

In a first-of-its-kind clinical trial, UCLA scientists have shown it’s possible to reprogram a patient’s blood-forming stem cells to generate a continuous supply of functional T cells, the immune ...